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• Activity deltas table
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Motif ID: TFAP2{A,C}.p2

Z-value: 3.538

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_39573363	6.734	NM_002220	ITPKA	inositol 1,4,5-trisphosphate 3-kinase A
chr3_-_130807865	5.888	NM_015103	PLXND1	plexin D1
chr15_-_81113676	4.804	NM_030594	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr15_+_64782468	4.789		SMAD6	SMAD family member 6
chr19_-_11452439	4.700	NM_001420 NM_032281	ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr4_+_2031036	4.519	NM_178557	NAT8L	N-acetyltransferase 8-like (GCN5-related, putative)
chr12_+_109956210	4.409	NM_015267	CUX2	cut-like homeobox 2
chr9_+_125813849	4.320		LHX2	LIM homeobox 2
chr3_-_129689394	4.205	NM_001145662	GATA2	GATA binding protein 2
chr9_+_94987032	4.117	NM_006648	WNK2	WNK lysine deficient protein kinase 2
chr19_+_540849	4.045	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr1_+_1557419	3.963	NM_006983	MMP23B	matrix metallopeptidase 23B
chr5_+_170668892	3.734	NM_021025	TLX3	T-cell leukemia homeobox 3
chr16_-_87535106	3.726	NM_175931	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr12_+_2032649	3.703	NM_000719 NM_001129827 NM_001129829 NM_001129830 NM_001129831 NM_001129832 NM_001129833 NM_001129834 NM_001129835 NM_001129836 NM_001129837 NM_001129838 NM_001129839 NM_001129840 NM_001129841 NM_001129842 NM_001129843 NM_001129844 NM_001129846 NM_001167623 NM_001167624 NM_001167625 NM_199460	CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit
chr8_-_144583718	3.597	NM_201589	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr2_+_120820140	3.559	NM_002193	INHBB	inhibin, beta B
chr1_-_11674264	3.521	NM_001127325	MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)
chrX_+_68641802	3.336	NM_015686	FAM155B	family with sequence similarity 155, member B
chr8_+_104582151	3.293	NM_001100117	RIMS2	regulating synaptic membrane exocytosis 2
chr10_-_88116181	3.288	NM_017551	GRID1	glutamate receptor, ionotropic, delta 1
chr3_+_182912769	3.214		SOX2	SRY (sex determining region Y)-box 2
chr22_-_37569679	3.207
chr4_-_41848874	3.204		BEND4	BEN domain containing 4
chr10_-_28074752	3.203	NM_173576	MKX	mohawk homeobox
chr10_+_94439658	3.203	NM_002729	HHEX	hematopoietically expressed homeobox
chr2_+_42128521	3.171	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr17_+_62391216	3.154	NM_014405	CACNG4	calcium channel, voltage-dependent, gamma subunit 4
chr5_+_149526533	3.154	NM_001804	CDX1	caudal type homeobox 1
chr1_+_41022066	3.129	NM_004700 NM_172163	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chr14_-_64416307	3.123		SPTB	spectrin, beta, erythrocytic
chr7_-_100331417	3.043	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr17_+_56831951	3.041	NM_005994	TBX2	T-box 2
chr3_+_50217692	3.037	NM_006841	SLC38A3	solute carrier family 38, member 3
chr10_-_131652364	3.002		EBF3	early B-cell factor 3
chr2_-_47650973	2.990	NM_022055	KCNK12	potassium channel, subfamily K, member 12
chr12_+_52665196	2.989	NM_017409	HOXC10	homeobox C10
chr18_+_53253775	2.985	NM_004852	ONECUT2	one cut homeobox 2
chr3_-_124650081	2.958	NM_183357	ADCY5	adenylate cyclase 5
chr4_-_85638410	2.939	NM_006168	NKX6-1	NK6 homeobox 1
chr10_-_134449467	2.860	NM_177400	NKX6-2	NK6 homeobox 2
chr3_+_148610516	2.854		ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)
chr2_+_74595073	2.818	NM_016170	TLX2	T-cell leukemia homeobox 2
chr20_-_538909	2.799	NM_004609	TCF15	transcription factor 15 (basic helix-loop-helix)
chr9_-_93751900	2.781	NM_004560	ROR2	receptor tyrosine kinase-like orphan receptor 2
chr11_-_60819110	2.778		VWCE	von Willebrand factor C and EGF domains
chr22_-_37569962	2.759	NM_014293	NPTXR	neuronal pentraxin receptor
chr17_+_45993338	2.742	NM_018896 NM_198376 NM_198377 NM_198378 NM_198379 NM_198380 NM_198382 NM_198383 NM_198384 NM_198385 NM_198386 NM_198387 NM_198388 NM_198396 NM_198397	CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit
chr2_+_102602579	2.719	NM_003048	SLC9A2	solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr10_+_23521464	2.718	NM_178161	PTF1A	pancreas specific transcription factor, 1a
chr2_-_45090025	2.668	NM_016932	SIX2	SIX homeobox 2
chr1_+_95355415	2.659	NM_152487	TMEM56	transmembrane protein 56
chr4_+_4912272	2.595	NM_002448	MSX1	msh homeobox 1
chr17_+_56832255	2.594		TBX2	T-box 2
chr17_-_77512346	2.588	NM_178493	NOTUM	notum pectinacetylesterase homolog (Drosophila)
chr20_-_21326046	2.570	NM_033176	NKX2-4	NK2 homeobox 4
chr20_+_20296744	2.531	NM_002196	INSM1	insulinoma-associated 1
chr16_+_2461500	2.522	NM_006181	NTN3	netrin 3
chr10_-_103525646	2.509	NM_006119 NM_033163 NM_033164 NM_033165	FGF8	fibroblast growth factor 8 (androgen-induced)
chr8_+_1937711	2.504		KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr1_-_50661716	2.491	NM_032110	DMRTA2	DMRT-like family A2
chr3_+_71885890	2.473	NM_018971	GPR27	G protein-coupled receptor 27
chr17_+_29931880	2.464	NM_207313	TMEM132E	transmembrane protein 132E
chr17_-_10042579	2.445	NM_201433	GAS7	growth arrest-specific 7
chr19_+_12805747	2.438		MAST1	microtubule associated serine/threonine kinase 1
chr2_-_42573980	2.433		KCNG3	potassium voltage-gated channel, subfamily G, member 3
chr20_+_19141364	2.421		SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr7_-_150306169	2.419		KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr5_-_11956964	2.411	NM_001332	CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr1_-_6162669	2.395	NM_015557	CHD5	chromodomain helicase DNA binding protein 5
chr19_-_14177980	2.386	NM_001008701 NM_014921	LPHN1	latrophilin 1
chr5_-_11957127	2.354		CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr9_+_128416542	2.336	NM_001174146 NM_001174147 NM_002316	LMX1B	LIM homeobox transcription factor 1, beta
chr17_-_44058612	2.327	NM_024017	HOXB9	homeobox B9
chr22_-_45311730	2.316	NM_014246	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr13_+_24844084	2.308	NM_016529	ATP8A2	ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr4_-_174687104	2.301		HAND2	heart and neural crest derivatives expressed 2
chr22_+_28446288	2.294	NM_182527	CABP7	calcium binding protein 7
chr1_-_110414756	2.292	NM_006492	ALX3	ALX homeobox 3
chr21_+_33364420	2.274		OLIG1	oligodendrocyte transcription factor 1
chr3_+_129690735	2.271
chr1_-_31154023	2.255	NM_014654	SDC3	syndecan 3
chr1_+_11674365	2.247	NM_198545	C1orf187	chromosome 1 open reading frame 187
chr2_+_171280944	2.240		SP5	Sp5 transcription factor
chr9_-_119217147	2.229		ASTN2	astrotactin 2
chr16_+_88169612	2.225	NM_014427 NM_153636	CPNE7	copine VII
chr22_+_43476710	2.220	NM_181333	PRR5	proline rich 5 (renal)
chr15_+_39008822	2.219	NM_019074	DLL4	delta-like 4 (Drosophila)
chr16_+_85158357	2.196	NM_005251	FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr9_+_125813672	2.192	NM_004789	LHX2	LIM homeobox 2
chr11_-_60819273	2.191	NM_152718	VWCE	von Willebrand factor C and EGF domains
chr17_+_8865547	2.188	NM_004822	NTN1	netrin 1
chr2_+_176695658	2.180	NM_014213	HOXD9	homeobox D9
chr2_+_176680251	2.175	NM_021192	HOXD11	homeobox D11
chr18_-_42590989	2.168	NM_013305	ST8SIA5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr1_+_22909916	2.154	NM_004442 NM_017449	EPHB2	EPH receptor B2
chr13_+_111769913	2.152	NM_005986	SOX1	SRY (sex determining region Y)-box 1
chr1_+_235272324	2.148	NM_001035	RYR2	ryanodine receptor 2 (cardiac)
chr4_+_48180033	2.147	NM_152679	SLC10A4	solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr3_-_71886203	2.146	NM_001134649	EIF4E3	eukaryotic translation initiation factor 4E family member 3
chr16_-_49742651	2.145	NM_002968	SALL1	sal-like 1 (Drosophila)
chr22_+_43476755	2.138	NM_181334	PRR5-ARHGAP8 PRR5	PRR5-ARHGAP8 readthrough proline rich 5 (renal)
chr6_+_19945578	2.137	NM_001546	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr17_+_40655060	2.128	NM_005892	FMNL1	formin-like 1
chr2_-_236741352	2.108	NM_001485	GBX2	gastrulation brain homeobox 2
chr20_-_62151216	2.071	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr16_+_166678	2.069	NM_000558	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr1_-_99242765	2.060	NM_001010861 NM_001037317	LPPR5	lipid phosphate phosphatase-related protein type 5
chr11_-_69299351	2.055	NM_002007	FGF4	fibroblast growth factor 4
chr11_+_43920385	2.033	NM_001145033	C11orf96	chromosome 11 open reading frame 96
chr19_+_10392128	2.027	NM_001111307	PDE4A	phosphodiesterase 4A, cAMP-specific
chr14_+_68796621	2.025		GALNTL1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr1_+_2975590	2.024	NM_022114 NM_199454	PRDM16	PR domain containing 16
chr15_+_30797466	2.014	NM_001191322 NM_001191323 NM_013372	GREM1	gremlin 1
chr11_-_1549719	2.012	NM_004420	DUSP8	dual specificity phosphatase 8
chr22_-_17891777	1.993		CLDN5	claudin 5
chr14_+_69021149	1.989	NM_001161498	UPF0639	UPF0639 protein
chr4_+_185064799	1.978		STOX2	storkhead box 2
chr5_-_134397740	1.968	NM_002653	PITX1	paired-like homeodomain 1
chr18_-_4445265	1.967		DLGAP1	discs, large (Drosophila) homolog-associated protein 1
chrX_-_139414890	1.960	NM_005634	SOX3	SRY (sex determining region Y)-box 3
chr19_+_51059357	1.950	NM_004497	FOXA3	forkhead box A3
chr17_-_16335809	1.945		C17orf76	chromosome 17 open reading frame 76
chr16_-_19803606	1.944	NM_016235	GPRC5B	G protein-coupled receptor, family C, group 5, member B
chr4_-_5945596	1.937	NM_001014809	CRMP1	collapsin response mediator protein 1
chr3_+_182912405	1.930	NM_003106	SOX2	SRY (sex determining region Y)-box 2
chr19_-_54557450	1.928	NM_003598	TEAD2	TEA domain family member 2
chr13_-_101366995	1.927	NM_004115	FGF14	fibroblast growth factor 14
chr12_+_108636569	1.922	NM_032829	C12orf34	chromosome 12 open reading frame 34
chr11_-_63292688	1.916	NM_001144936	C11orf95	chromosome 11 open reading frame 95
chr15_+_82113813	1.907	NM_207517	ADAMTSL3	ADAMTS-like 3
chr5_-_1348103	1.902	NM_001193376 NM_198253	TERT	telomerase reverse transcriptase
chr10_-_99780336	1.895		CRTAC1	cartilage acidic protein 1
chr14_-_76677711	1.888		ZDHHC22	zinc finger, DHHC-type containing 22
chr6_-_110786167	1.885	NM_001123364	C6orf186	chromosome 6 open reading frame 186
chr16_-_51138306	1.884	NM_001080430	TOX3	TOX high mobility group box family member 3
chr8_-_57521702	1.883	NM_001135690	PENK	proenkephalin
chr7_-_150305933	1.865	NM_000238 NM_172056	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr7_+_94374862	1.860	NM_001166160 NM_017650	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr3_+_185580554	1.857	NM_003741	CHRD	chordin
chr4_-_174686918	1.842		HAND2	heart and neural crest derivatives expressed 2
chr9_-_95757365	1.841	NM_021570	BARX1	BARX homeobox 1
chr10_-_131652007	1.825	NM_001005463	EBF3	early B-cell factor 3
chr12_+_2032964	1.801		CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit
chr17_-_71747867	1.797	NM_052916	RNF157	ring finger protein 157
chr10_+_50488352	1.794	NM_003055	SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3
chr15_-_49174107	1.792		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr12_+_79995927	1.790	NM_024560	ACSS3	acyl-CoA synthetase short-chain family member 3
chr2_-_219633481	1.783	NM_002181	IHH	Indian hedgehog
chr1_+_226937732	1.782		RHOU	ras homolog gene family, member U
chr19_+_1704661	1.782	NM_001080488	ONECUT3	one cut homeobox 3
chr19_+_39664706	1.778	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr7_-_35260213	1.771	NM_001077653 NM_001166220	TBX20	T-box 20
chr11_-_61441536	1.768	NM_013401	RAB3IL1	RAB3A interacting protein (rabin3)-like 1
chr1_+_229365296	1.757	NM_001004342	TRIM67	tripartite motif containing 67
chr7_-_123460722	1.754	NM_001136002	TMEM229A	transmembrane protein 229A
chr1_-_114497994	1.751	NM_205848	SYT6	synaptotagmin VI
chr20_-_61108831	1.748	NM_080606	BHLHE23	basic helix-loop-helix family, member e23
chr6_+_5030718	1.744	NM_001145115	PPP1R3G	protein phosphatase 1, regulatory (inhibitor) subunit 3G
chr4_-_13155135	1.743	NM_001189	NKX3-2	NK3 homeobox 2
chr1_+_63561632	1.741		FOXD3	forkhead box D3
chr22_-_37180958	1.733	NM_152868	KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4
chr11_+_65311104	1.733	NM_004561	OVOL1	ovo-like 1(Drosophila)
chr2_-_42574587	1.714	NM_133329 NM_172344	KCNG3	potassium voltage-gated channel, subfamily G, member 3
chr18_+_46340400	1.714	NM_002747	MAPK4	mitogen-activated protein kinase 4
chr6_+_99389318	1.709		POU3F2	POU class 3 homeobox 2
chr7_+_154943466	1.697	NM_001427	EN2	engrailed homeobox 2
chr14_-_100104014	1.697	NM_001159531	BEGAIN	brain-enriched guanylate kinase-associated homolog (rat)
chr9_+_966963	1.695	NM_021240	DMRT3	doublesex and mab-3 related transcription factor 3
chr2_+_241586927	1.694	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr2_+_176702667	1.692	NM_019558	HOXD8	homeobox D8
chr4_+_72271218	1.687	NM_001098484 NM_001134742	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chrX_-_53367246	1.687	NM_001111125	IQSEC2	IQ motif and Sec7 domain 2
chr8_+_56177567	1.681	NM_052898	XKR4	XK, Kell blood group complex subunit-related family, member 4
chr8_-_71146022	1.679		PRDM14	PR domain containing 14
chr17_+_56832492	1.677		TBX2	T-box 2
chr10_+_29006425	1.675	NM_012342	BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
chr22_-_43783449	1.674		PHF21B	PHD finger protein 21B
chr21_+_36993860	1.667	NM_005069 NM_009586	SIM2	single-minded homolog 2 (Drosophila)
chr1_-_111019051	1.666
chr14_+_28306633	1.658		FOXG1	forkhead box G1
chr16_+_162845	1.656	NM_000517	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr5_+_129268352	1.654	NM_175856	CHSY3	chondroitin sulfate synthase 3
chr5_+_76542461	1.654	NM_001029851 NM_001029852 NM_001029853 NM_001029854 NM_003719	PDE8B	phosphodiesterase 8B
chr2_+_172658453	1.652	NM_001038493 NM_178120	DLX1	distal-less homeobox 1
chr14_+_89597860	1.649	NM_022054	KCNK13	potassium channel, subfamily K, member 13
chr6_-_117193505	1.649	NM_001085480	FAM162B	family with sequence similarity 162, member B
chr16_+_52877009	1.645
chr11_-_18769703	1.642	NM_001039970 NM_006906 NM_032781	PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr13_+_87122778	1.642	NM_015567	SLITRK5	SLIT and NTRK-like family, member 5
chr9_-_95757448	1.641		BARX1	BARX homeobox 1
chr3_+_50687675	1.638	NM_004947	DOCK3	dedicator of cytokinesis 3
chr11_+_63815348	1.635	NM_033310	KCNK4	potassium channel, subfamily K, member 4
chr2_-_222871577	1.627	NM_000438 NM_001127366 NM_013942 NM_181457 NM_181458 NM_181459 NM_181460 NM_181461	PAX3	paired box 3
chr10_+_101079099	1.625		CNNM1	cyclin M1
chr3_-_50515857	1.620	NM_001005505 NM_001174051 NM_006030	CACNA2D2	calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr7_-_27206249	1.608	NM_000522	HOXA13	homeobox A13
chr11_-_31796061	1.608	NM_001127612	PAX6	paired box 6
chr2_+_231610438	1.601	NM_001144994	C2orf72	chromosome 2 open reading frame 72
chr9_+_138858687	1.588	NM_001080482	C9orf172	chromosome 9 open reading frame 172

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.67	1.66e-30	GO:0048731	system development
3.60	3.70e-30	GO:0007399	nervous system development
2.43	1.91e-29	GO:0007275	multicellular organismal development
2.33	3.28e-29	GO:0032502	developmental process
2.48	7.60e-28	GO:0048856	anatomical structure development
3.27	9.35e-24	GO:0009653	anatomical structure morphogenesis
4.90	9.53e-22	GO:0009887	organ morphogenesis
2.73	4.40e-21	GO:0030154	cell differentiation
1.86	2.43e-20	GO:0032501	multicellular organismal process
2.65	4.53e-20	GO:0048869	cellular developmental process
4.38	6.23e-20	GO:0009790	embryo development
6.16	3.22e-19	GO:0007389	pattern specification process
2.72	8.00e-19	GO:0048513	organ development
5.71	7.06e-18	GO:0048598	embryonic morphogenesis
2.28	7.22e-17	GO:0031326	regulation of cellular biosynthetic process
3.66	1.54e-16	GO:0048699	generation of neurons
3.56	1.68e-16	GO:0022008	neurogenesis
4.69	1.81e-16	GO:0007417	central nervous system development
2.26	1.85e-16	GO:0009889	regulation of biosynthetic process
2.27	2.16e-16	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.02	2.62e-16	GO:0030182	neuron differentiation
3.52	2.98e-16	GO:0048468	cell development
2.41	1.34e-15	GO:0006355	regulation of transcription, DNA-dependent
2.37	2.40e-15	GO:0051252	regulation of RNA metabolic process
2.20	2.56e-15	GO:0051171	regulation of nitrogen compound metabolic process
2.28	3.64e-15	GO:0010556	regulation of macromolecule biosynthetic process
2.30	4.19e-15	GO:2000112	regulation of cellular macromolecule biosynthetic process
6.58	9.57e-15	GO:0003002	regionalization
2.21	3.63e-14	GO:0010468	regulation of gene expression
1.55	2.49e-13	GO:0050794	regulation of cellular process
1.89	3.43e-12	GO:0031323	regulation of cellular metabolic process
1.94	3.61e-12	GO:0060255	regulation of macromolecule metabolic process
3.06	5.70e-12	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.50	7.08e-12	GO:0050789	regulation of biological process
4.77	1.00e-11	GO:0007420	brain development
1.88	1.64e-11	GO:0080090	regulation of primary metabolic process
3.19	1.64e-11	GO:0009888	tissue development
7.48	1.80e-11	GO:0045165	cell fate commitment
1.44	1.18e-10	GO:0065007	biological regulation
3.99	2.42e-10	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
5.05	4.42e-10	GO:0007423	sensory organ development
2.96	6.17e-10	GO:0050793	regulation of developmental process
4.36	7.88e-10	GO:0009792	embryo development ending in birth or egg hatching
3.20	8.10e-10	GO:2000026	regulation of multicellular organismal development
3.34	9.99e-10	GO:0010628	positive regulation of gene expression
5.43	1.22e-09	GO:0048568	embryonic organ development
3.32	1.26e-09	GO:0045595	regulation of cell differentiation
4.65	1.60e-09	GO:0001501	skeletal system development
1.74	1.68e-09	GO:0019222	regulation of metabolic process
4.95	1.78e-09	GO:0035295	tube development
6.10	1.82e-09	GO:0035239	tube morphogenesis
3.88	2.54e-09	GO:0048646	anatomical structure formation involved in morphogenesis
4.28	2.91e-09	GO:0043009	chordate embryonic development
3.38	3.92e-09	GO:0045893	positive regulation of transcription, DNA-dependent
6.53	3.97e-09	GO:0048562	embryonic organ morphogenesis
5.38	4.12e-09	GO:0002009	morphogenesis of an epithelium
4.21	4.71e-09	GO:0060429	epithelium development
7.71	6.09e-09	GO:0043583	ear development
2.09	6.67e-09	GO:0048523	negative regulation of cellular process
2.49	1.01e-08	GO:0051239	regulation of multicellular organismal process
4.62	1.05e-08	GO:0048729	tissue morphogenesis
3.61	2.08e-08	GO:0000904	cell morphogenesis involved in differentiation
5.90	3.17e-08	GO:0030900	forebrain development
1.99	3.37e-08	GO:0048519	negative regulation of biological process
3.15	3.92e-08	GO:0051254	positive regulation of RNA metabolic process
2.97	5.48e-08	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
6.03	5.90e-08	GO:0009952	anterior/posterior pattern formation
4.28	6.84e-08	GO:0051093	negative regulation of developmental process
3.33	7.10e-08	GO:0048666	neuron development
4.70	9.00e-08	GO:0045596	negative regulation of cell differentiation
1.94	1.00e-07	GO:0048522	positive regulation of cellular process
2.88	1.50e-07	GO:0051173	positive regulation of nitrogen compound metabolic process
4.21	2.11e-07	GO:0060284	regulation of cell development
8.62	2.18e-07	GO:0021953	central nervous system neuron differentiation
8.62	2.18e-07	GO:0042471	ear morphogenesis
3.09	2.21e-07	GO:0010558	negative regulation of macromolecule biosynthetic process
3.20	2.30e-07	GO:0000902	cell morphogenesis
12.06	2.31e-07	GO:0048663	neuron fate commitment
3.11	3.11e-07	GO:0032989	cellular component morphogenesis
3.77	3.58e-07	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
6.37	5.96e-07	GO:0048705	skeletal system morphogenesis
5.88	7.94e-07	GO:0060562	epithelial tube morphogenesis
2.83	1.18e-06	GO:0010557	positive regulation of macromolecule biosynthetic process
1.82	1.23e-06	GO:0048518	positive regulation of biological process
2.90	1.45e-06	GO:0009890	negative regulation of biosynthetic process
2.69	1.46e-06	GO:0031328	positive regulation of cellular biosynthetic process
3.21	1.93e-06	GO:0045892	negative regulation of transcription, DNA-dependent
2.64	2.51e-06	GO:0009891	positive regulation of biosynthetic process
2.99	2.57e-06	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.89	2.62e-06	GO:0031327	negative regulation of cellular biosynthetic process
6.16	3.07e-06	GO:0001763	morphogenesis of a branching structure
3.14	3.30e-06	GO:0051253	negative regulation of RNA metabolic process
2.41	5.33e-06	GO:0010646	regulation of cell communication
9.15	7.34e-06	GO:0050768	negative regulation of neurogenesis
8.10	8.18e-06	GO:0007498	mesoderm development
11.95	8.75e-06	GO:0001708	cell fate specification
2.06	1.06e-05	GO:0023051	regulation of signaling
2.93	1.23e-05	GO:0010629	negative regulation of gene expression
3.16	1.43e-05	GO:0031175	neuron projection development
5.24	1.46e-05	GO:0006813	potassium ion transport
6.44	1.47e-05	GO:0061138	morphogenesis of a branching epithelium
6.96	1.65e-05	GO:0030326	embryonic limb morphogenesis
6.96	1.65e-05	GO:0035113	embryonic appendage morphogenesis
4.23	1.89e-05	GO:0050767	regulation of neurogenesis
6.81	2.22e-05	GO:0048839	inner ear development
3.33	2.25e-05	GO:0007409	axonogenesis
3.93	3.59e-05	GO:0051960	regulation of nervous system development
6.52	3.92e-05	GO:0048754	branching morphogenesis of a tube
3.22	4.92e-05	GO:0032583	regulation of gene-specific transcription
3.22	4.92e-05	GO:0048667	cell morphogenesis involved in neuron differentiation
2.43	4.97e-05	GO:0010605	negative regulation of macromolecule metabolic process
2.81	5.59e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.32	6.51e-05	GO:0007154	cell communication
3.16	7.19e-05	GO:0048812	neuron projection morphogenesis
2.78	7.64e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
3.41	7.85e-05	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
3.00	7.99e-05	GO:0048858	cell projection morphogenesis
7.48	8.08e-05	GO:0010721	negative regulation of cell development
6.13	8.69e-05	GO:0035107	appendage morphogenesis
6.13	8.69e-05	GO:0035108	limb morphogenesis
2.98	9.72e-05	GO:0032990	cell part morphogenesis
9.41	1.06e-04	GO:0021510	spinal cord development
5.90	1.43e-04	GO:0048736	appendage development
5.90	1.43e-04	GO:0060173	limb development
2.68	1.80e-04	GO:0030030	cell projection organization
2.51	1.89e-04	GO:0007267	cell-cell signaling
3.46	2.01e-04	GO:0007411	axon guidance
3.45	2.14e-04	GO:0045597	positive regulation of cell differentiation
4.40	2.21e-04	GO:0048732	gland development
2.39	2.39e-04	GO:0040011	locomotion
2.35	2.59e-04	GO:0031324	negative regulation of cellular metabolic process
7.49	2.86e-04	GO:0042472	inner ear morphogenesis
3.03	2.96e-04	GO:0051094	positive regulation of developmental process
6.64	3.17e-04	GO:0021915	neural tube development
7.26	3.94e-04	GO:0009953	dorsal/ventral pattern formation
4.19	4.60e-04	GO:0045664	regulation of neuron differentiation
2.25	4.74e-04	GO:0009892	negative regulation of metabolic process
3.42	8.31e-04	GO:0022603	regulation of anatomical structure morphogenesis
2.07	1.24e-03	GO:0031325	positive regulation of cellular metabolic process
2.03	1.26e-03	GO:0009893	positive regulation of metabolic process
4.92	1.40e-03	GO:0030111	regulation of Wnt receptor signaling pathway
1.51	1.57e-03	GO:0023052	signaling
22.11	1.82e-03	GO:0032332	positive regulation of chondrocyte differentiation
6.16	2.17e-03	GO:0048706	embryonic skeletal system development
2.85	2.59e-03	GO:0023057	negative regulation of signaling
2.84	2.71e-03	GO:0010648	negative regulation of cell communication
3.18	2.73e-03	GO:0015672	monovalent inorganic cation transport
7.66	3.04e-03	GO:0007190	activation of adenylate cyclase activity
7.51	3.59e-03	GO:0031281	positive regulation of cyclase activity
7.51	3.59e-03	GO:0045762	positive regulation of adenylate cyclase activity
13.97	3.76e-03	GO:0035137	hindlimb morphogenesis
6.51	3.91e-03	GO:0001657	ureteric bud development
2.14	3.93e-03	GO:0042127	regulation of cell proliferation
7.24	4.95e-03	GO:0051349	positive regulation of lyase activity
10.32	5.15e-03	GO:0021515	cell differentiation in spinal cord
18.43	5.52e-03	GO:0003382	epithelial cell morphogenesis
2.19	5.84e-03	GO:0006351	transcription, DNA-dependent
9.99	6.52e-03	GO:0061351	neural precursor cell proliferation
2.00	6.59e-03	GO:0010604	positive regulation of macromolecule metabolic process
8.04	7.66e-03	GO:0009880	embryonic pattern specification
5.41	8.01e-03	GO:0021537	telencephalon development
1.75	9.54e-03	GO:0007166	cell surface receptor linked signaling pathway
12.06	9.75e-03	GO:0032330	regulation of chondrocyte differentiation
7.53	1.28e-02	GO:0001649	osteoblast differentiation
15.80	1.34e-02	GO:0045686	negative regulation of glial cell differentiation
3.05	1.48e-02	GO:0007610	behavior
1.85	1.57e-02	GO:0009966	regulation of signal transduction
4.62	1.59e-02	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
4.00	1.62e-02	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter
11.06	1.69e-02	GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway
8.60	1.88e-02	GO:0048332	mesoderm morphogenesis
3.51	2.08e-02	GO:0043193	positive regulation of gene-specific transcription
8.37	2.27e-02	GO:0002064	epithelial cell development
22.11	2.31e-02	GO:0030917	midbrain-hindbrain boundary development
6.03	2.32e-02	GO:0042476	odontogenesis
4.82	2.45e-02	GO:0010720	positive regulation of cell development
2.57	2.47e-02	GO:0072358	cardiovascular system development
2.57	2.47e-02	GO:0072359	circulatory system development
3.63	2.56e-02	GO:0032582	negative regulation of gene-specific transcription
8.15	2.73e-02	GO:0001658	branching involved in ureteric bud morphogenesis
13.82	2.83e-02	GO:0021846	cell proliferation in forebrain
4.35	2.91e-02	GO:0010769	regulation of cell morphogenesis involved in differentiation
4.32	3.15e-02	GO:0022604	regulation of cell morphogenesis
2.01	3.20e-02	GO:0032879	regulation of localization
2.57	3.52e-02	GO:0008283	cell proliferation
7.74	3.88e-02	GO:0001656	metanephros development
7.74	3.88e-02	GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway
7.74	3.88e-02	GO:0010578	regulation of adenylate cyclase activity involved in G-protein signaling pathway
7.74	3.88e-02	GO:0010579	positive regulation of adenylate cyclase activity by G-protein signaling pathway
19.66	4.08e-02	GO:0021903	rostrocaudal neural tube patterning
4.18	4.35e-02	GO:0001503	ossification
2.48	4.36e-02	GO:0030001	metal ion transport
9.48	4.39e-02	GO:0072006	nephron development
6.32	4.84e-02	GO:0021543	pallium development
3.62	4.91e-02	GO:0035270	endocrine system development

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
2.86	4.64e-04	GO:0045202	synapse
3.29	1.78e-03	GO:0005667	transcription factor complex
4.26	2.02e-03	GO:0034703	cation channel complex
5.09	4.45e-03	GO:0008076	voltage-gated potassium channel complex
5.09	4.45e-03	GO:0034705	potassium channel complex
2.93	5.24e-03	GO:0044456	synapse part
2.61	3.60e-02	GO:0005578	proteinaceous extracellular matrix
2.45	3.79e-02	GO:0031012	extracellular matrix
2.98	4.81e-02	GO:0034702	ion channel complex

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
3.74	1.75e-22	GO:0001071	nucleic acid binding transcription factor activity
3.74	1.75e-22	GO:0003700	sequence-specific DNA binding transcription factor activity
4.44	4.51e-22	GO:0043565	sequence-specific DNA binding
3.62	2.80e-21	GO:0030528	transcription regulator activity
1.97	7.07e-09	GO:0003677	DNA binding
3.71	2.99e-06	GO:0016563	transcription activator activity
3.68	7.02e-06	GO:0022836	gated channel activity
5.62	7.44e-06	GO:0005267	potassium channel activity
3.86	1.07e-05	GO:0005261	cation channel activity
4.50	1.48e-05	GO:0005244	voltage-gated ion channel activity
4.50	1.48e-05	GO:0022832	voltage-gated channel activity
3.02	1.80e-04	GO:0005216	ion channel activity
4.67	2.32e-04	GO:0022843	voltage-gated cation channel activity
2.97	2.42e-04	GO:0022838	substrate-specific channel activity
1.54	3.79e-04	GO:0003676	nucleic acid binding
2.88	4.29e-04	GO:0015267	channel activity
2.88	4.50e-04	GO:0022803	passive transmembrane transporter activity
4.97	3.83e-03	GO:0005249	voltage-gated potassium channel activity
2.39	4.43e-03	GO:0008324	cation transmembrane transporter activity
12.29	1.12e-02	GO:0005109	frizzled binding
3.29	1.69e-02	GO:0000975	regulatory region DNA binding
3.29	1.69e-02	GO:0001067	regulatory region nucleic acid binding
3.29	1.69e-02	GO:0044212	transcription regulatory region DNA binding
2.06	2.12e-02	GO:0015075	ion transmembrane transporter activity
3.19	4.02e-02	GO:0010843	promoter binding